PERAN PENTING MIOKIN MELALUI LATIHAN FISIK PADA LANJUT USIA

Authors

I Gusti Putu Suka Aryana
RSUP Sanglah
Sandra Surya Rini
RSUD Kabupaten Lombok Utara

Keywords:

Miokin, lanjut usia

Synopsis

Miokin adalah peptida yang diproduksi, diekspresikan, dan dilepaskan oleh otot yang dapat bekerja secara autokrin, parakrin atau endokrin. Otot skeletal merupakan organ terbesar dalam tubuh manusia, sehingga miokin yang diproduksi melalui kontraksi otot membuka suatu paradigma baru mengenai peran sentral otot dalam mengatur metabolisme dan fungsi organ lainnya. Beberapa penelitian menujukkan bahwa miokin yang diinduksi melalui latihan fisik memiliki efek “polypill” dengan manfaat yang sangat luas bukan hanya mencegah sarkopenia, namun juga dalam penyakit kronik dan degeneratif.

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